Table 2.

Initial Hemodynamic Parameters

Variable	Placebo (n=16)	DPP4 Inhibition (n=14)
DPP4 activity, U/L	27.3±4.5	9.8±5.7*
DPP4 antigen, ng/mL	417.7±90.0	386.3±91.3
Systolic blood pressure, mm Hg	109.3±8.3	115.1±8.7*
Diastolic blood pressure, mm Hg	67.5±7.0	68.9±8.3
Mean arterial pressure, mm Hg	84.1±5.9	86.7±6.5
Heart rate, bpm	56.8±9.2	57.4±8.5
FVR, mm Hg/mL per minute per 100 mL	36.3±18.1	29.8±12.7*
FBF, mL/min per 100 mL	2.7±0.9	3.5±1.5*

Results are presented as mean±SD. bpm indicates beats per minute; DPP4, dipeptidyl peptidase 4; FBF, forearm blood flow; FVR, forearm vascular resistance.

^*P<0.05 vs placebo.