Table 6.
Multivariable Logistic Models for the Prediction of ICU Mortality and 12‐Month Poor Outcome
| OR | 95% CI | P Value | |
|---|---|---|---|
| ICU death | |||
| TRP | 0.994 per 1 μmol/L increase | 0.970 to 1.018 | 0.614 |
| KYN | 1.431 per 1 μmol/L increase | 1.136 to 1.803 | 0.002 |
| KYN to TRP | 1.665 per 1 SD increase | 1.143 to 2.426 | 0.0079 |
| KYNA | 1.005 per 1 nmol/L increase | 1.002 to 1.007 | 0.0007 |
| 3‐HAA | 1.013 per 1 nmol/L increase | 1.005 to 1.021 | 0.0015 |
| 12‐month poor outcome | |||
| TRP | 1.007 per 1 μmol/L increase | 0.985 to 1.030 | 0.519 |
| KYN | 1.249 per 1 μmol/L increase | 0.982 to 1.588 | 0.069 |
| KYN to TRP | 1.251 per 1 SD increase | 0.798 to 1.963 | 0.329 |
| KYNA | 1.004 per 1 nmol/L increase | 1.001 to 1.008 | 0.0139 |
| 3‐HAA | 1.011 per 1 nmol/L increase | 1.001 to 1.022 | 0.0272 |
3‐HAA indicates 3‐hydroxyanthranilic acid; ICU, intensive care unit; KYN, kynurenine; KYNA, kynurenic acid; OR, odds ratio; TRP, tryptophan.