Table 5.
Adjusted Hazard Ratios for Myocardial Infarction by Smoking. The Tromsø Study 1994–2010
| Person‐Years | Events | Model 1* | Model 2* | Model 3* | |
|---|---|---|---|---|---|
| HR (95% CI) | HR (95% CI) | HR (95% CI) | |||
| Nonsmokers | |||||
| Quintile 1 | 47 657 | 105 | Reference | Reference | Reference |
| Quintile 2 | 42 381 | 140 | 1.04 (0.81 to 1.35) | 1.00 (0.78 to 1.30) | 0.97 (0.75 to 1.26) |
| Quintile 3 | 41 602 | 166 | 1.02 (0.80 to 1.31) | 0.93 (0.72 to 1.19) | 0.87 (0.68 to 1.12) |
| Quintile 4 | 38 209 | 250 | 1.32 (1.04 to 1.66) | 1.22 (0.97 to 1.54) | 1.16 (0.91 to 1.46) |
| Quintile 5 | 41 483 | 383 | 1.47 (1.17 to 1.83) | 1.34 (1.07 to 1.68) | 1.21 (0.96 to 1.53) |
| >95th percentile | 8972 | 80 | 1.63 (1.21 to 2.18) | 1.55 (1.14 to 2.11) | 1.30 (0.94 to 1.80) |
| Smokers | |||||
| Quintile 1 | 20 793 | 53 | Reference | Reference | Reference |
| Quintile 2 | 21 168 | 86 | 1.24 (0.88 to 1.74) | 1.25 (0.89 to 1.77) | 1.25 (0.88 to 1.77) |
| Quintile 3 | 23 864 | 124 | 1.39 (1.01 to 1.93) | 1.37 (0.99 to 1.91) | 1.31 (0.94 to 1.82) |
| Quintile 4 | 26 127 | 161 | 1.26 (0.93 to 1.74) | 1.25 (0.91 to 1.72) | 1.22 (0.88 to 1.68) |
| Quintile 5 | 33 109 | 307 | 1.52 (1.14 to 2.06) | 1.52 (1.12 to 2.06) | 1.43 (1.05 to 1.95) |
| >95th percentile | 5800 | 71 | 2.01 (1.41 to 2.89) | 2.49 (1.71 to 3.63) | 2.28 (1.55 to 3.35) |
Adjusted HRs with 95% CI for myocardial infarction across quintiles and values above the 95‐percentile (>14.3%) for red cell distribution width among smokers and nonsmokers. HR indicates hazard ratio.
*
Model 1: Age was used as time scale.
*
Model 2: Model 1 plus sex, body mass index, hemoglobin, white blood cells, and platelets.
*
Model 3: Model 2 plus hypertension, total cholesterol, triglycerides, red blood cell count, and self‐reported diabetes.