Table 6.
Stroke Subtypes According to Vascular Territory in This Study and the Lausanne and Besançon Stroke Registries
| Mechanism* | ACA | MCA | ICA* | PCA | Brainstem | Cerebellum | BZ | Multiple | Total* |
|---|---|---|---|---|---|---|---|---|---|
| LAA | |||||||||
| Our study | 65.3 | 34.2 | 51.5 | 28.7 | 40.1 | 48.4 | 89.9 | 32.4 | 37.3 |
| Lausanne | 50.0 | 44.4 | 12.5 | 35.0 | 38.0 | 53.0 | 79.0 | 27.0 | 43.2 |
| Besançon | 20.0 | 27.8 | 34.8 | 25.9 | 43.3 | 34.7 | 35.3 | 31.1 | 30.5 |
| SVO | |||||||||
| Our study | 0.0 | 25.6 | 0.0 | 36.1 | 44.4 | 0.0 | 0.0 | 0.0 | 22.9 |
| Lausanne | 0.0 | 15.6 | 0.0 | 9.0 | 25.0 | 6.0 | 0.0 | 19.0 | 13.2 |
| Besançon | 2.9 | 1.3 | 13.9 | 0.0 | 16.5 | 0.0 | 0.9 | 2.3 | 10.0 |
| CE | |||||||||
| Our study | 10.2 | 22.8 | 33.3 | 19.1 | 5.8 | 21.9 | 5.1 | 32.2 | 20.6 |
| Lausanne | 35.0 | 18.8 | 0.0 | 25.0 | 6.0 | 29.0 | 9.0 | 15.0 | 20.4 |
| Besançon | 45.7 | 43.4 | 22.2 | 41.0 | 17.5 | 33.3 | 27.6 | 30.5 | 31.0 |
| OD | |||||||||
| Our study | 2.0 | 1.7 | 0.0 | 3.0 | 3.0 | 3.1 | 1.3 | 6.9 | 2.9 |
| Lausanne | 5.0 | 7.9 | 62.5 | 13.0 | 17.0 | 12.0 | 4.0 | 31.0 | 10.6 |
| Besançon | 0.0 | 2.0 | 1.4 | 1.2 | 1.0 | 5.8 | 5.2 | 4.0 | 2.5 |
| UD | |||||||||
| Our study | 22.5 | 15.7 | 15.2 | 13.1 | 6.7 | 26.6 | 3.8 | 28.5 | 16.2 |
| Lausanne | 10.0 | 13.7 | 25.0 | 18.0 | 14.0 | 0.0 | 8.0 | 8.0 | 12.6 |
| Besançon | 38.5 | 25.3 | 27.8 | 31.8 | 21.6 | 26.1 | 31.0 | 32.2 | 26.1 |
Due to differences in the ethnicity of the study population, the study time period, the modality of brain imaging, and the methods of etiologic evaluation, careful interpretation of results should be made. Values are percentages of patients. ACA indicates anterior cerebral artery; BZ, border zone infarction; CE, cardioembolism; ICA, internal carotid artery; LAA, large‐artery atherosclerosis; MCA, middle cerebral artery; Multiple, multiple‐territory infarction; OD, other determined etiology; PCA, posterior cerebral artery; SVO, small vessel occlusion; UD, undetermined etiology.
Mechanism: Our study used stroke subtypes using the Trial of ORG 10172 in Acute Stroke Treatment (TOAST) to categorize stroke mechanism. The Lausanne and Besançon stroke registries used different stroke mechanism categories. Stroke mechanism categories from previous studies were modified as follows. Lausanne stroke registry: LAA, atherosclerosis with stenosis and atherosclerosis without stenosis; SVO, hypertensive arteriolopathy; CE, emboligenic heart disease; OD, other etiology‐arterial dissection and other etiologies; UD, Combined etiology‐atherosclerosis with stenosis and emboligenic heart disease, Combined etiology‐hypertensive arteriolopathy and emboligenic heart disease, and undetermined etiology. Besançon stroke registry: LAD, large vessel disease and atheroma with no stenosis; SVO, small vessel disease; CE, cardioembolism; OD, dissection; UD, combined, miscellaneous, and undetermined.
ICA: Definition of ICA territory infarction was different among studies: our study, when anterior choroidal artery or the entire ICA territory was involved; Lausanne stroke registry: when entire ICA territory was involved; Besançon stroke registry: when anterior choroidal artery was involved.
Total: Our study and the Lausanne stroke registry included only patients with visible stroke lesion in imaging studies. The Besançon stroke registry also included patients with no visible stroke lesion on imaging studies. Consequently, in the total category, the Besançon stroke registry contains data from patients without stroke lesion.