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Time-dependent changes in the concentration of artocarpin in (a) HSC-1 cells (intracellular compartment) and (b) culture medium (extracellular compartment) under different concentrations of FBS. Artocarpin concentration in the two different compartments was determined by HPLC-UV analysis after treatment of cells with artocarpin (10 μM) for different periods of time. Results are mean ± SEM of 3 independent experiments.
