Figure 2.
ADAMTS-7 and TNF-α are upregulated in ONFH patients. (a) Expression of ADAMTS-7 of cartilage samples of FNF patients and ONFH patients at different stages, assayed by immunohistochemistry. (b) Expression of TNF-α in different groups, examined by immunohistochemistry with anti-TNF-α serum. (c) Quantitative analysis of ADAMTS-7-positive area of each group. (d) Quantitative analysis of TNF-α area of each group. Statistically significant increases in the expression of ADAMTS-7 and TNF-α were observed in group II and group III compared with group I (* P < 0.05, ** P < 0.01). Significant increases in the ADAMTS-7 and TNF-α expression were observed in group III compared with group II (# P < 0.05, ## P < 0.01).