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. 2015 Jan 29;10(1):e0116343. doi: 10.1371/journal.pone.0116343

Figure 17. Schematic representation of the temporal-spatial correlation between OT angiogenesis and corticogenesis.

Figure 17

OT angiogenesis is composed of two phases. The first phase (DS1-DS3) corresponds to the elaboration of a primitive vascular plexus associated to the generation of macroneurons and establishment of the deep OT layers (SGC and SGP). The second phase implies an intensive remodeling of the primitive vascular plexus and the establishment of the definitive OT vascular plexus. This phase is associated to the formation of the microneurons and its organization into the multilayered pattern of SGFS.