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Primary sequences of IAPP and the IAPP variants studied here. The residues that differ from those of wild-type IAPP are colored red. Wild-type IAPP and IAPP variants, with the exception of Ac 8–37-IAPP, all contain a disulfide bond between Cys-2 and Cys-7. All peptides contain an amidated C-terminus. The structure of resveratrol is also shown.
