Table 2.

Urinary flow and MAP in control and diabetic rats with and without chronic CoCl₂ treatment during baseline and after acute administration of tempol

Group	N	Urinary Flow (µl/min per kidney)		MAP (mmHg)
		Baseline	Tempol	Baseline	Tempol
Control	9	2.6±0.5	3.0±0.5	116±3	105±2a
Control+CoCl2	9	2.2±0.3	1.9±0.6	106±3b	92±2a,b
Diabetes	12	30.2±7.6b	21.6±4.2b	105±2b	97±1a
Diabetes+CoCl2	10	21.7±6.2b	15.7±4.8a,b	102±2b	93±4a,b
Two-way ANOVA
Type		P<0.001	P<0.001	P=0.01	P=0.17
Treatment		P=0.44	P=0.32	P=0.03	P<0.01
Interaction		P=0.48	P=0.50	P=0.15	P=0.08

All values are ±SEM. Type denotes control versus diabetes, and treatment denotes untreated versus CoCl₂.

^aP<0.05 compared with baseline within the same group.

^bP<0.05 compared with the untreated control group.