Table 2.
Performance of the three assays to predict allograft loss at 1 and 3 years after AMR
| Variable | C4d Graft Deposition (%) | C1q-Binding Assay (%) | C3d-Binding Assay (%) |
|---|---|---|---|
| Graft loss at 1 year post-rejection | |||
| Sensitivity | 80.0 | 60.0 | 90.0 |
| Specificity | 45.5 | 48.5 | 51.5 |
| Positive predictive value | 47.1 | 41.4 | 52.9 |
| Negative predictive value | 78.9 | 66.7 | 89.5 |
| Graft loss at 3 years post-rejection | |||
| Sensitivity | 69.2 | 61.5 | 84.6 |
| Specificity | 40.0 | 60.0 | 73.3 |
| Positive predictive value | 66.7 | 72.7 | 84.6 |
| Negative predictive value | 42.9 | 47.4 | 73.3 |