. Author manuscript; available in PMC: 2015 Jan 29.

Published in final edited form as: Am J Ophthalmol. 2013 Mar 14;155(6):971–982. doi: 10.1016/j.ajo.2013.01.020

Table 7.

Differences in Rate of Rim Area Change in eyes with a Ocular Hypertension Treatment Study Visual Field Primary Open Angle Glaucoma Endpoint compared to eyes with an Optic Disc Primary Open Angle Glaucoma Endpoint only or Optic Disc Change (not necessarily a Primary Open Angle Glaucoma endpoint)

Visual Field and Op.c Disc Change Criteria	N (eyes)	Slope (95% CI) (mm²/yr)	P-Value^#	P-Value comparing slopes to VF POAG Endpoint slope	P-Value comparing slopes to Not at POAG endpoint slope
Not at POAG Endpoint	731	−0.0021 (−0.0031, −0.0011)	<0.0001	0.1655	NA
Visual Field POAG Endpoint	21	−0.0079 (−0.0157, −0.0001)	0.0513	NA	0.1655
Optic Disc POAG Endpoint Only^*	45	−0.0169 (−0.0225, −0.0113)	<0.0001	0.0426	0.0001
Optic Disc Reading Center Change (POAG and not POAG)^*	72	−0.0131 (−0.0178, −0.0084)	<0.0001	0.1433	0.0001
Optic Disc Reading Center Change NOT POAG Endpoint^*	27	−0.0094 (−0.0161, −0.0027)	0.0063	0.54	0.0012

Does not include the 1 eye that had both a POAG visual field endpoint and a POAG optic disc

p-value to evaluate whether the slope is significantly different from zero

POAG: Primary Open Angle Glaucoma