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. Author manuscript; available in PMC: 2016 Jan 31.
Published in final edited form as: Drug Alcohol Depend. 2014 Dec 30;147:32–37. doi: 10.1016/j.drugalcdep.2014.12.019

Table 3.

Relative risk of death in older (≥50 years) adults with opioid use disorder, compared to younger (<50 years) adults with opioid use disorder and older (≥50 years) adults without opioid use disorder, VA patients, FY2000–2011

Relative risk (95% CI) of death in older adults with
opioid use disorder (n=36,608), compared to:

Cause of death Younger opioid use
disorder (n=23,662)a
Older no opioid use
disorder (n=36,608)b
All cause 2.2 (2.2, 2.3) 1.6 (1.5, 1.6)
Drug-related 0.8 (0.8, 0.9) 8.6 (8.0, 9.3)
Accidental drug-related 0.9 (0.8, 1.0) 9.5 (8.7, 10.3)
Suicide 1.0 (0.8, 1.1) 2.1 (1.7, 2.4)
Violence 0.6 (0.4, 0.8) 2.0 (1.3, 2.7)
Accidental injuries 1.7 (1.4, 1.9) 1.8 (1.5, 2.0)
Cancer 4.3 (4.1, 4.5) 1.3 (1.2, 1.3)
HIV 1.2 (1.0, 1.4) 2.7 (2.2, 3.2)
Cardiovascular disease 2.8 (2.7, 3.0) 1.3 (1.2, 1.4)
Liver-related 2.3 (2.2, 2.4) 3.0 (2.8, 3.1)
Chronic respiratory disease 4.5 (4.1, 4.9) 1.7 (1.5, 1.8)
Respiratory infections 3.4 (2.8, 4.1) 1.5 (1.2, 1.8)
Diabetes 2.2 (1.9, 2.5) 0.9 (0.8, 1.1)

CI=confidence interval.

a

Older opioid use disorder CMR/younger opioid use disorder CMR.

b

Older opioid use disorder CMR/Older, no opioid use disorder CMR. Sex-disaggregated data are provided in the Supplementary Materials3.