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. 2015 Feb 1;26(3):583–590. doi: 10.1091/mbc.E14-08-1267

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© 2015 Hughey, Gutschow, et al. This article is distributed by The American Society for Cell Biology under license from the author(s). Two months after publication it is available to the public under an Attribution–Noncommercial–Share Alike 3.0 Unported Creative Commons License (http://creativecommons.org/licenses/by-nc-sa/3.0).

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FIGURE 1: — The time between p65-dsRed nuclear localization peaks is constant across stimuli and concentration. (A) The fraction of active cells (top row), as well as the time to (second row) and amplitude of (third row) the first peak, vary, depending on stimulus and concentration, whereas the time between the first and second peaks (bottom row) is constant. (B) Distributions of all interpeak times for five different environmental conditions: TNF and LPS (concentrations as shown in A), LPS (concentrations as shown in A), together with soluble TNF receptor II (sTNFR; 5 μg/ml), Pam3CSK4 (1 μg/ml), and Sendai virus (10 and 100 U/ml). See also Supplemental Figure S1.