Table 2.
Plasma sphingomyelins and dihydrosphingomyelins cross-sectionally by age and sex at the Baltimore Longitudinal Study of Aging visit in the present analyses
| Plasma Sphingomyelins (ng mL−1 ×104) | Aged 55–64 years |
Aged 65–74 years |
Aged ≥75 years |
||||||
|---|---|---|---|---|---|---|---|---|---|
| N | Mean (SD) | Range | N | Mean (SD) | Range | N | Mean (SD) | Range | |
| Sphingomyelins | |||||||||
| C16:0 | |||||||||
| Women | 212 | 51.87 (14.97) | 22.37–98.67 | 105 | 53.77 (13.81) | 17.71–93.51 | 49 | 57.02 (17.56) | 26.03–102.41 |
| Men | 431 | 51.19 (17.03) | 10.67–117.20 | 127 | 53.72 (16.17) | 17.41–109.62 | 67 | 51.00 (15.68) | 21.66–100.43 |
| C18:0 | |||||||||
| Women | 212 | 7.76 (2.90)c | 2.42–18.77 | 105 | 8.24 (2.72)b | 2.31–15.62 | 48 | 8.29 (3.14)b | 2.87–18.67 |
| Men | 430 | 6.84 (2.63) | 1.30–15.63 | 126 | 7.30 (2.66) | 2.09–15.35 | 67 | 6.94 (1.98) | 3.42–13.06 |
| C20:0 | |||||||||
| Women | 211 | 8.63 (3.10)b | 3.02–21.74 | 105 | 9.13 (2.71) | 4.09–15.27 | 49 | 9.12 (3.22) | 4.26–18.41 |
| Men | 431 | 7.97 (2.86) | 1.24–21.41 | 127 | 8.87 (3.27) | 3.13–19.16 | 67 | 8.12 (2.31) | 3.03–12.86 |
| C22:0 | |||||||||
| Women | 210 | 11.83 (5.02) | 3.20–33.39 | 105 | 12.13 (4.15) | 3.91–23.12 | 49 | 12.37 (5.12) | 3.15–24.69 |
| Men | 429 | 11.59 (5.08) | 2.03–32.77 | 127 | 12.97 (5.74) | 3.88–29.28 | 67 | 11.9 (4.42) | 5.06–25.42 |
| C24:0 | |||||||||
| Women | 210 | 10.08 (4.57) | 3.07–28.39 | 105 | 10.53 (4.09) | 3.97–22.64 | 49 | 10.34 (4.22) | 2.37–22.18.00 |
| Men | 429 | 9.94 (4.46) | 2.07–28.99 | 127 | 10.89 (4.58) | 3.26–24.23 | 67 | 10.3 (4.21) | 4.26–27.48 |
| C16:1 | |||||||||
| Women | 212 | 7.10 (2.20)c | 2.60–15.43 | 105 | 7.54 (2.45)a | 2.77–14.52 | 49 | 7.49 (2.15)c | 4.56–15.00 |
| Men | 431 | 6.15 (2.04) | 1.48–14.90 | 127 | 6.78 (2.07) | 2.77–13.83 | 67 | 6.24 (1.66) | 2.22–10.49 |
| C18:1 | |||||||||
| Women | 209 | 20.37 (8.18)c | 4.78–51.99 | 105 | 20.88 (7.34) | 5.38–45.55 | 47 | 20.86 (8.72) | 6.93–46.92 |
| Men | 429 | 17.41 (7.48) | 4.5–50.02 | 125 | 20.52 (8.55) | 6.03–45.35 | 67 | 18.29 (6.66) | 8.94–45.71 |
| C20:1 | |||||||||
| Women | 212 | 3.57 (1.58)c | 1.33–8.79 | 105 | 3.73 (1.54)a | 0.82–8.87 | 49 | 3.93 (1.64)c | 1.98–9.06 |
| Men | 431 | 2.83 (1.15) | 0.63–8.07 | 127 | 3.35 (1.32) | 1.15–7.38 | 67 | 3.04 (1.02) | 1.17–6.46 |
| C22:1 | |||||||||
| Women | 211 | 12.96 (4.98)c | 3.39–28.62 | 105 | 13.34 (4.67) | 3.33–27.34 | 49 | 14.3 (5.95)b | 6.66–32.59 |
| Men | 431 | 11.05 (4.58)a | 1.87–34.05 | 127 | 12.28 (5.02) | 3.74–31.62 | 67 | 11.61 (4.4) | 4.51–22.71 |
| C24:1 | |||||||||
| Women | 211 | 24.87 (9.77) | 10.97–64.34 | 105 | 26.63 (9.03) | 9.97–52.56 | 49 | 27.56 (12.02) | 12.37–67.73 |
| Men | 431 | 22.98 (9.84) | 6.22–69.00 | 127 | 26.29 (10.16) | 10.07–68.90 | 67 | 25.1 (8.65) | 10.87–54.87 |
| DihydoSphingomyelins | |||||||||
| C16:0 | |||||||||
| Women | 211 | 1.08 (0.44)b | 0.26–2.66 | 105 | 1.11 (0.47) | 0.36–2.70 | 49 | 1.27 (0.46)c | 0.46–2.25 |
| Men | 432 | 0.96 (0.43) | 0.13–2.47 | 127 | 1.00 (0.40) | 0.27–2.23 | 67 | 0.99 (0.39) | 0.37–2.59 |
| C18:0 | |||||||||
| Women | 212 | 21.40 (8.16) | 4.07–50.10 | 105 | 22.03 (8.18) | 7.08–54.52 | 49 | 22.59 (7.45) | 7.74–39.72 |
| Men | 431 | 20.13 (8.09) | 1.53–55.98 | 126 | 24.04 (9.42) | 0.96–58.40 | 67 | 24.73 (8.86) | 11.37–55.04 |
| C22:0 | |||||||||
| Women | 211 | 0.74 (0.38) | 0.18–2.06 | 102 | 0.79 (0.35) | 0.27–1.95 | 48 | 0.80 (0.45) | 0.17–2.13 |
| Men | 428 | 0.73 (0.38) | 0.14–2.09 | 127 | 0.76 (0.42) | 0.08–2.20 | 66 | 0.76 (0.37) | 0.25–1.77 |
| C24:0 | |||||||||
| Women | 209 | 1.70 (0.70) | 0.57–4.46 | 105 | 1.85 (0.71) | 0.64–4.00 | 49 | 1.78 (0.77) | 0.53–4.60 |
| Men | 428 | 1.69 (0.74) | 0.41–4.52 | 127 | 1.78 (0.73) | 0.61–4.70 | 67 | 1.71 (0.69) | 0.63–4.18 |
T-tests used to compare cross-sectional sex differences within each age group.
a
P < 0.05
b
P < 0.01
c
P < 0.001.