. Author manuscript; available in PMC: 2016 Jan 31.

Published in final edited form as: Obesity (Silver Spring). 2014 Dec 17;23(2):468–474. doi: 10.1002/oby.20950

Table 3.

Risk Ratios (and 95% CI) for Nonalcoholic Fatty Liver Disease^a by Age at Menarche in Women from CARDIA.

	Age at menarche (years)

	8–<12 (n=293)	12–<14 (n=692)	14–18 (n=230)	1-yr earlier menarche
Cases	74	132	29
Model 1	1 (referent)	0.77 (0.61, 0.99)	0.49 (0.33, 0.72)	1.15 (1.07, 1.24)
Model 2	1 (referent)	0.83 (0.65, 1.06)	0.59 (0.40, 0.87)	1.10 (1.02, 1.19)
Model 3	1 (referent)	0.87 (0.68, 1.12)	0.71 (0.49, 1.04)	1.06 (0.98, 1.15)

Model 1: Adjusted for birthdate, race, study center, parental education, maternal diabetes, paternal diabetes, pre-high school physical activity, year 0 smoking status (never, former, current), and year 0 diet score.

Model 2: Model 1 + adjustment for BMI at year 0 exam.

Model 3: Model 2 + adjustment for weight change between year 0 and year 25.

Nonalcoholic fatty liver disease is defined by liver attenuation < 51 Hounsfield units.