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. Author manuscript; available in PMC: 2015 Nov 1.
Published in final edited form as: Mech Ageing Dev. 2014 Oct 22;0:64–69. doi: 10.1016/j.mad.2014.10.002

Table 3.

Prospective association of telomere length (T/S ratio) with amnestic MCI

Model 1
 Model 2
Variable Cases
N (%)		 Controls
N (%)		 Hazard Ratio
(95% CI)		 p
Value		 Hazard Ratio
(95% CI)		 p
Value
Matched analysisa
T/S quintiles
  Q1: <0.43 27 (19.9) 22 (16.2) 2.85 (0.98, 8.25) 0.05 2.54 (0.88, 7.32) 0.09
  Q2: 0.43 – 0.59 28 (20.6) 31 (22.8) 2.02 (0.79, 5.18) 0.14 1.95 (0.77, 4.92) 0.16
  Q3: 0.59 – 0.78 20 (14.7) 32 (23.5) 1.00 (reference) -- 1.00 (reference) --
  Q4: 0.78 – 1.16 23 (16.9) 31 (22.8) 1.45 (0.54, 3.92) 0.47 1.42 (0.52, 3.83) 0.49
  Q5: > 1.16 38 (27.9) 20 (14.7) 5.58 (2.21, 14.11) 0.0003 5.04 (1.98, 12.84) 0.0007
a

Proportional hazards models for nested case-control analyses stratified on matched pairs. Model 1 was adjusted for education; Model 2 also included APOE ε4 allele and type 2 diabetes.