Table 4. Identifying predictors of acute coronary syndrome in patients with GCA at incidence.

Variables	Hazard ratio (95% CI)	P-value
GCA symptoms and signs:
PMR symptoms	1.53 (0.66, 3.51)	0.318
Fever >100	1.80 (0.71, 4.57)	0.218
Weight loss	0.41 (0.10, 1.74)	0.225
Jaw claudication	0.73 (0.32, 1.65)	0.444
Scalp tenderness	0.76 (0.33, 1.75)	0.515
Tender temporal artery	0.64 (0.22, 1.82)	0.400
Temporal artery biopsy positivity#	0.87 (0.19, 3.88)	0.85
Transient vision loss	1.16 (0.15, 8.79)	0.888
Permanent vision loss*	-	-
Bruit	1.06 (0.14, 8.17)	0.953
Aortitis*	-	-
ESR, mm/hr	1.01 (0.99, 1.02)	0.245
Comorbidities:
Smoking	0.45 (0.16, 1.28)	0.136
Hypertension before GCA incidence	0.88 (0.36, 2.16)	0.778
Diabetes mellitus before GCA incidence	0.00 (0.00,)	0.990
Coronary artery disease before GCA incidence	0.31 (0.04, 2.39)	0.262
Transient ischemic attack/stroke before GCA incidence	1.92 (0.57, 6.49)	0.293
Medications:
Steroid sparing disease modifying agent use (time-dependent)	1.36 (0.53, 3.53)	0.524
Starting dose of glucocorticoid	0.99 (0.96, 1.02)	0.476
Cumulative glucocorticoid dose in the first year (per 1 gm increase)	1.03 (0.86, 1.22)	0.749

^*No patients with permanent vision loss or aortitis had acute coronary syndrome

^#89% of the GCA cohort was temporal artery biopsy positive