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. Author manuscript; available in PMC: 2015 Nov 1.
Published in final edited form as: Mech Ageing Dev. 2014 Sep 10;0:12–21. doi: 10.1016/j.mad.2014.08.003

Table 3.

Comparion of the cellular localization of ABCB1, ABCC1, 5´-nucleotidase (5´-N), adenosine deaminase (ADA) and nucleoside triphosphate diphosphohydrolase-2 (NTPDase2)

Brain
structure
ABCB1 ABCC1 5´-N ADA NTPDase2
(analysed in
detail only in
the habenula)
cingulate
cortex
few neurons,
fibers
fibers few neurons,
fibers
Numerous
neurons, fibers
hippocampus interneurons,
neuropil
surrounding
pyramidal cells of
CA3 region
single fibers neuropil
surrounding
pyramidal cells
single pyramidal
cells,
interneurons,
fibers
habenula small-sized
neurons, fibers
(medial habenula),
fibers (lateral
habenula)
small-sized
neurons, a few
fibers (medial
habenula)
small-sized
neurons, fibers
(medial
habenula),
fibers (lateral
habenula)
small-sized
neurons, fibers
(medial
habenula),
neurons and
fibers (lateral
habenula)
immunoreactive
(nonstellate;
Gampe et al. 2012) astrocyte
cell bodies
“forming thin
cellular sheats
that surround
neuronal cell
bodies”
lateral
geniculate
numerous
neurons, fibers
single
neurons, fibers
fibers numerous
neurons, fibers
hypothalamus son: single
neurons
pvn: numerous
magnocellular
neurons
scn: single
neurons
son: single
neurons
pvn: numerous
neurons
scn: single
neurons;
numerous
astrocytes
son : none
pvn : single
neurons, fibers
scn : fibers
son : none
pvn : single
neurons, fibers
scn : fibers
Substantia
nigra
neurons, dense
fibers
dense fibers dense fibers neurons, dense
fibers
ventral
tegmental area
dense fibers dense fibers dense fibers dense fibers
periaqueductal
gray
dense fibers fibers fibers fibers
Locus
coeruleus
single neurons,
fibers
some fibers some fibers fibers
cerebellum some Purkinje
cells, Golgi 1 and
2 cells,
some granule
cells,
fibers
some granule
cells, fibers
fibers some Purkinje
cells
granule cells,
fibers