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Obesity stimulates vascular arginase activity and expression, and plasma arginase activity. Obesity increases arginase activity in the aorta (A), arginase (Arg) I and II, but not endothelial nitric oxide synthase (eNOS), mRNA expression in gracilis muscle arterioles (B), and arginase activity in the plasma (C). Results are means ± SEM (n=4–5). *Statistically significant effect of obesity.
