Table 2. Univariate and multivariate analysis for overall survival.
| Univariate analysis | Multivariate analysis | ||||||||
| HR | 95% CI | P value | HR | 95% CI | P value | ||||
| Age (/year) | 1.05 | 1.02 | 1.07 | <0.001 | 1.05 | 1.02 | 1.08 | <0.001 | |
| Sex | Female | reference | reference | ||||||
| Male | 2.71 | 1.64 | 4.46 | <0.001 | 2.28 | 1.34 | 3.88 | 0.002 | |
| Smoking status | Never | reference | reference | ||||||
| Ever/Current | 1.16 | 1.01 | 1.32 | 0.03 | 1.26 | 1.02 | 1.55 | 0.029 | |
| CEA (ng/mL) | ≤5 | reference | reference | ||||||
| >5 | 2.56 | 1.71 | 3.82 | <0.001 | 1.09 | 0.99 | 1.19 | 0.052 | |
| Operative procedure | Wedge/Seg | reference | reference | ||||||
| Lob | 0.69 | 0.39 | 1.19 | 0.185 | 0.69 | 0.38 | 1.26 | 0.224 | |
| Pn | 1.1 | 0.47 | 2.6 | 0.827 | 0.68 | 0.25 | 1.91 | 0.47 | |
| Histology | AD | reference | reference | ||||||
| SQ | 2.3 | 1.52 | 3.49 | <0.001 | 1.55 | 0.95 | 2.53 | 0.08 | |
| Others | 2.16 | 1.15 | 4.07 | 0.017 | 1.98 | 0.99 | 3.91 | 0.05 | |
| p-stage | I | reference | reference | ||||||
| II | 2.12 | 1.27 | 3.56 | 0.004 | 2.21 | 1.26 | 3.89 | 0.006 | |
| III | 2.99 | 1.9 | 4.72 | <0.001 | 5.78 | 3.42 | 9.76 | <0.001 | |
| Adjuvant therapy | No | reference | reference | ||||||
| Yes | 0.56 | 0.32 | 0.98 | 0.031 | 0.45 | 0.24 | 0.82 | 0.01 | |
| Blood group | O | reference | reference | ||||||
| A | 1.88 | 1.15 | 3.08 | 0.012 | 2.47 | 1.45 | 4.21 | 0.001 | |
| B | 1.55 | 0.84 | 2.87 | 0.164 | 1.47 | 0.77 | 2.79 | 0.244 | |
| AB | 1.98 | 0.94 | 4.17 | 0.071 | 3.62 | 1.61 | 8.15 | 0.002 | |
AD, adenocarcinoma; CEA, carcinoembryonic antigen; CI, confidence interval; HR, hazard ratio; Lob, lobectomy; Pn, pneumonectomy; p-stage, pathological stage; Seg, segmentectomy; SQ, squamous cell carcinoma; Wedge, wedge resection.