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. 2013 Dec 22;23(1):55–66. doi: 10.1016/j.jsps.2013.12.007

Table 4.

Fractional inhibitory concentration (FIC) indices of AMB/FLC and AMB/VOC combinations against candida isolates.

Combined antibiotics tested FIC indices
Synergistic reaction Additive reaction Indifferent reaction Antagonistic reaction
(FIC < 1) (FIC = 1) (1 > FIC ⩽ 4) (FIC > 4)
% (No) FIC range % (No) FIC % (No) FIC range % (No) FIC range
AMB/FLC 12.2% (6) 43.5% (20) 12.2% (6) 34.7% (17)
(0.1–0.4) (1) (1.4–1.7) (5–44)



AMB/VOC 32.7% (16) 36.7% (18) 12.2% (6) 18.4% (9)
(0.04–0.4) (1) (1.2–1.8) (4.2–18.5)