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. 2014 Dec 10;7(6):741–751. doi: 10.1016/j.tranon.2014.09.004

Figure 4.

Figure 4

Figure 4

The post-translational regulation of telomerase activity in response to Brt exposure. Cells were exposed to the IC50 of Brt and the phosphorylation status of hTERT, PKCα and AKT were measured by IP and Western blot. A, Phospho-hTERT expression in MCL cells. B, C. D. Examples of Western blot results for HBL-2, NCEB and mononuclear cells isolated from a MCL patient respectively; E, F, G. Quantitation of the results (obtained after three repetitions and measurements of three MCL patients), respectively. H, I. The cellular levels of PP2A in HBL-2 and NCEB cells, respectively.