Table 1. Demographic, baseline disease, and treatment characteristics for the entire cohort (n=62) and broken down by whether or not patients received adjuvant therapy following surgical resection.
Characteristic | All patients (n=62) | Patients who received adjuvant therapy (n=39) | Patients who did not receive adjuvant therapy (n=23) | P value |
---|---|---|---|---|
Demographic data | ||||
Age: median [IQR] | 68 [57-77] | 67 [55-76] | 68 [65-80] | 0.107 |
Age ≥65 years: No. (%) | 38 [61] | 21 [54] | 17 [74] | 0.177 |
Gender: No. male (%) | 35 [56] | 23 [59] | 12 [52] | 0.791 |
ECOG performance status ≥1: No. (%) | 13 [21] | 10 [26] | 3 [13] | 0.338 |
Tumor resection specimen data | ||||
Tumor diameter: median centimeters (IQR) | 4.0 (3.0-6.0) | 4.5 (3.5-6.0) | 4.0 (3.0-6.3) | 0.645 |
Tumor diameter: No. >3 cm [%] | 45 [73] | 30 [77] | 15 [65] | 0.383 |
Histologic grade | ||||
No. well differentiated [%] | 0 [0] | 0 [0] | 0 [0] | – |
No. moderately differentiated [%] | 11 [18] | 6 [15] | 5 [22] | 0.732 |
No. poorly differentiated [%] | 51 [82] | 33 [85] | 18 [78] | 0.732 |
Tumor stage | ||||
No. T2 [%] | 10 [16] | 7 [18] | 3 [13] | 0.731 |
No. T3 [%] | 41 [66] | 24 [62] | 17 [73] | 0.409 |
No. T4 [%] | 11 [18] | 8 [21] | 3 [13] | 0.516 |
Lymph node involvement at resection: No. [%] | 48 [77] | 31 [79] | 17 [74] | 0.755 |
Positive margin at resection: No. [%] | 18 [29] | 11 [28] | 7 [30] | 0.999 |
Lymphovascular invasion present: No. [%] | 46 [74] | 28 [72] | 18 [78] | 0.765 |
Perineural invasion present: No. [%] | 52 [84] | 31 [79] | 21 [54] | 0.298 |
The right-most column shows P values for statistical comparison of each characteristic between patients who did (n=39) and did not (n=23) receive adjuvant therapy in the form of chemoradiation or chemotherapy alone. IQR, interquartile range; No., number; ECOG, Eastern Cooperative Oncology Group; cGy, centiGray.