Table 3.
Intervention group (n=103) | Control group (n=98) | t | p | ||
---|---|---|---|---|---|
daily dose in mg mean (sd) |
daily dose in mg mean (sd) |
||||
baseline | 184 (27) | 192 (31) | 1.34 | 0.181 | |
follow-upb | 203 (28) | 187 (30) | 3.91 | 0.001 |
aBefore and after comparison of the intervention group, paired-t=4.15, p<0.001; before and after comparison of the control group, paired-t=0.66, p=0.255; for the overall repeated measures analysis of variance F=9.54, p=0.002
bThis was an intention-to-treat analysis; the last observed value (i.e., the value at baseline) was carried forward and used as the 30-month follow-up value for the 4 subjects who dropped out of the intervention group and for three subjects who dropped out of the control group