Table 3.
Comparisons of mean (sd) magnitude of before versus after changes in blood glucose and lipid levels after 8 weeks of treatment with olanzapine, quetiapine, and aripiprazole (n=50 for each group)
| olanzapine [O] mean(sd) |
quetiapine [Q] mean(sd) |
aripiprazole [A] mean(sd) |
statistica | p | multiple comparisonsb | |
|---|---|---|---|---|---|---|
| fasting blood glucose | 0.61(1.36) | -0.03(0.97) | 0.08(1.97) | X2=14.41 | 0.001 | O>A, Q |
| triglyceride | 0.81(1.48) | 0.77(1.43) | 0.22(0.72) | X2=7.37 | 0.025 | O, Q>A |
| total cholesterol | 0.15(1.19) | 0.34(1.11) | -0.01(0.99) | X2=1.26 | 0.532 | --- |
| low-density lipoprotein | 0.08(0.99) | 0.15(0.80) | -0.08(0.68) | X2=3.20 | 0.202 | --- |
| high-density lipoprotein | -0.26(0.35) | -0.14(0.26) | -0.02(0.28) | F=7.90 | <0.001 | --- |
aKruskal-Wallis test was used for non-normally distributed data
bIf the difference of the three groups was significant, post-hoc pairwise comparisons were conducted using the least significant difference (LSD) method for normally distributed variables and the Nemenyi test for non-normal variables