Table 4.
Results of repeated measures ANOVA of pre- and post-treatment assessment of measures in patients treated for 8 weeks with olanzapine, quetiapine, or aripiprazole (n=50 for each group)
| Measure | factor | F | p |
|---|---|---|---|
| fasting blood glucose |
time | 3.37 | 0.069 |
| group | 4.89 | 0.009 | |
| time*group | 2.63 | 0.075 | |
| triglyceride | time | 33.76 | <0.001 |
| group | 2.69 | 0.071 | |
| time*group | 3.39 | 0.036 | |
| total cholesterol | time | 3.22 | 0.075 |
| group | 3.70 | 0.027 | |
| time*group | 1.22 | 0.299 | |
| low-density lipoprotein |
time | 0.62 | 0.432 |
| group | 1.90 | 0.153 | |
| time*group | 1.01 | 0.369 | |
| high-density lipoprotein |
time | 32.74 | <0.001 |
| group | 0.66 | 0.517 | |
| time*group | 7.90 | 0.001 | |
| PANSS total score | time | 1005.70 | <0.001 |
| group | 0.77 | 0.465 | |
| time*group | 1.40 | 0.249 | |
| PANSS positive symptom score |
time | 467.32 | <0.001 |
| group | 0.780 | 0.461 | |
| time*group | 1.20 | 0.305 | |
| PANSS negative symptom score |
time | 471.54 | <0.001 |
| group | 1.89 | 0.155 | |
| time*group | 0.72 | 0.490 | |
| PANSS general psychopathology score |
time | 859.83 | <0.001 |
| group | 0.67 | 0.512 | |
| time*group | 2.78 | 0.065 |
PANSS, Positive and Negative Syndrome Scale