Table 1.
The levels and activities of various biochemical markers in the sera and spinal cord tissues of the experimental groups.
| Control (I) | I/R (II) | Atorvastatin (III) | Withdrawal (IV) | Statistical results* | |||
| Serum/Tissue | Variable | Mean±SD Median (IQR) | Mean±SD Median (IQR) | Mean±SD Median (IQR) | Mean±SD Median (IQR) | F/χ2 | p |
| SERUM | MDA (µmol/l) | 0.22±0.02 | 0.32±0.06 | 0.26±0.04 | 0.27±0.03 | F = 7.055 | 0.001 |
| SOD (U/ml) | 15.73±1.13 | 10.37±0.71 | 13.58±1.10 | 14.26±0.95 | F = 42.174 | <0.001 | |
| NO (µmol/l) | 9.90 (0.76) | 11.27 (0.89) | 7.56 (0.67) | 8.06 (1.12) | χ2 = 26.960 | <0.001 | |
| XO (U/ml) | 0.08 (0.02) | 0.20 (0.12) | 0.03 (0.08) | 0.06 (0.09) | χ2 = 17.356 | <0.001 | |
| TISSUE | MDA (µmol/g) | 17.28±0.87 | 25.77±0.40 | 19.67±0.52 | 21.56±0.59 | F = 267.705 | <0.001 |
| SOD (U/mg) | 0.18±0.02 | 0.53±0.12 | 0.32±0.03 | 0.48±0.04 | F = 45.455 | <0.001 | |
| NO (µmol/g) | 0.23 (0.08) | 1.19 (0.03) | 0.92 (0.29) | 1.06 (0.51) | χ2 = 19.472 | <0.001 | |
| XO (U/g) | 0.24 (0.15) | 0.85 (0.55) | 0.29 (0.07) | 0.25 (0.04) | χ2 = 20.367 | <0.001 | |
| MPO (mU/g) | 2.53±0.43 | 4.23±0.35 | 2.88±0.55 | 3.33±0.51 | F = 20.133 | <0.001 | |
| GSH-Px (U/g) | 0.59±0.07 | 0.52±0.06 | 0.57±0.03 | 0.62±0.04 | F = 4.899 | 0.007 | |
*F: based on an ANOVA; χ2: based on the Kruskal-Wallis test.