Table I.
Outcomes following hormonal stimulation and ICSI in nine couples where the men presented with type I globozoospermia due to the full deletion of the DPY19L2 gene.
| Patient number | M1 | G1-1 | G1-2 | G1-3 | T1.1 | T1.2 | T3 | T4 | T5.1 | T5.2 | T7 | T8 | T9 | Mean | SD |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Age, male (years) | 30 | 37 | 38 | 38 | 31 | 31 | 50 | 40 | 36 | 38 | 30 | 42 | 38 | ||
| Age, female (years) | 28 | 29 | 30 | 30 | 27 | 36 | 37 | 36 | 24 | 26 | 26 | 36 | 28 | 30.23 | 4.28 |
| Nber MII oocytes | 14 | 10 | 4 | 5 | 10 | 6 | 8 | 4 | 29 | 19 | 10 | 11 | 9 | ||
| Nber 2-PN embryos | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 10 | 1 | 1 | 1 | 1 | ||
| % of 2-PN embryos/MII* | 14.3 | 10 | 0 | 0 | 0 | 0 | 0 | 0 | 34.5 | 5.3 | 10 | 9 | 11.1 | 7.25 | 9.76 |
MII, metaphase II oocytes retrieved; PN, pronuclei.
*Oocyte activation rate upon ICSI in 13 different stimulation cycles.