Table 3.
Average (±SEM) Calculated Rates of Change in Metabolic Syndrome Parameters Measured in Monkeys Based on Baseline SkM Tissue HSP70 Levels
| Rate of Change | Low Baseline SkM HSP70 | High Baseline SkM HSP70 | p Value ANOVA |
|---|---|---|---|
| N | 28 | 13 | |
| Age at baseline (y) | 11.1 (0.62) | 11.5 (0.90) | .73 |
| Body weight (kg/y) | 0.10 (0.042) | 0.081 (0.055) | .78 |
| BMI (kg/m2/y) | 0.78 (0.23) | 0.72 (0.32) | .88 |
| Waist circumference (cm/y) | 0.49 (0.21) | 0.32 (0.34) | .64 |
| Glucose (mg/dL/y) | 13 (1.9) | 10 (1.7) | .37 |
| TG (mg/dL/y) | 9.9 (1.2) | 8.0 (1.2) | .31 |
| TPC (mg/dL/y) | 6.5 (0.87) | 3.2 (2.8) | .15 |
| HDL-C (mg/dL/y) | −6.38 (0.52) | −7.6 (1.1) | .28 |
| SBP (mmHg/y) | −2.8 (3.2) | −7.4 (3.2) | .39 |
| DBP (mmHg/y) | 13 (8.0) | −1.8 (1.4) | .23 |
Notes: ANOVA = analysis of variance; BMI = body mass index; DBP = diastolic blood pressure; HDL-C = high-density lipoprotein cholesterol; HSP70 = heat shock protein 70; SBP = systolic blood pressure; SkM = skeletal muscle; TG = triglyceride; TPC = total plasma cholesterol. High and low baseline SkM HSP70 was defined as being above or below the mean HSP70 measurement.