Figure 5.

Structure of the PSM from Representative Phys in Their Dark-Adapted States.

(A) Ribbon diagrams of PSMs from Syn-Cph1 (PDB code 2VEA), Pa-BphP (3C2W), and Dr-BphP (4Q0J) in their dark-adapted states. Helical spine is highlighted by the dashed red lines. Hairpin is located by the bracket. The paired subunits of the Pa-BphP and Dr-BphP dimers are in gray. Other coloring is as in Figure 3. The spectral state of each structure is indicated in parenthesis.

(B) SPEM model of the full-length Dr-BphP dimer. Only a portion of the histidine kinase domain was imaged due to conformational flexibility. The crystal structure of the PSM is included for one subunit with the space-filling model of the bilin shown.

([A] is adapted from data presented in Essen et al. [2008], Figure 1B; Yang et al. [2008], Figure 1A; and Burgie et al. [2014b], Figure 5A.)