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(a and b) Representative confocal images show hotspots of Aβ42-555 binding (arrowheads) in fresh unfixed (a) and fixed-permeabilized brain slices (b). (c) Immunohistochemistry with Aβ42 and Aβ40 c-terminus specific antibodies on fixed brain slices from mice that did not receive an Aβ-555 injections. Scale bars: 5μm in all panels.
