Table 1.
Antimicrobial activity of Ds-defensin
| Strain of microbes | MIC (μM) |
|---|---|
| Gram-positive bacteria | |
| Bacillus pumilus (CMCC63202) | 1 |
| Staphylococcus aureus (CMCC26003) | 20 |
| Micrococcus luteus (CMCC63202) | 50 |
| Mycobacterium bovis (carbenicillin-resistant) | 20 |
| Gram-negative bacteria | |
| Salmonella typhimurium (CVCC542) | >50 |
| Pseudomonas aeruginosa (CVCC2000) | >50 |
| Escherichia coli (CMCC44103) | no effect |
| Fungus | |
| Candida albicans (CAU0037) | >50 |
MIC: minimal peptide concentration required for total inhibition of cell growth in liquid medium. Determination of MICs was performed at least three times in triplicates.