Fig. 2.
Metabolic characteristics of WT and Dgat2Int mice fed chow or HFD. (A) Body weights of Dgat2Int and WT male mice fed chow diet from weaning to 18 wks of age, n = 12–14 mice. (B) Body weights of Dgat2Int and WT male mice fed HFD for 9 wks starting at 10 wks of age, n = 7–11 mice. Body weights were monitored weekly for the duration of the study. (C) Liver and gonadal fat pad weights of Dgat2Int and WT male mice fed chow diet from weaning to 18 wks of age or HFD for 9 wks starting at 10 wks of age, n = 12–14 mice and n = 7–11 mice, respectively. Mice were euthanized after a 2-h fast and liver and gonadal fat pad weight was measured. (D) 12 h fasting blood glucose and TG of Dgat2Int and WT male mice fed chow diet or HFD for 6 wks, n = 7–8 mice. Asterisk denotes significant difference compared to WT mice (T-test), P < 0.05.