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. 2015 Jan 30;9:4. doi: 10.3389/fncel.2015.00004

Figure 2.

Figure 2

Role of ionotropic glutamate receptors on radial migration in vivo and in vitro. (A) Digital photographs of Nissl-stained coronal sections from a P7 rat that received at P0 on the cortical surface an Elvax implant containing DMSO (A1, control) or an implant loaded with the NMDA antagonist MK801 (A2). Note abnormal cortical architecture and heterotopia in upper layers of the MK801-treated rat. (B) NMDA receptors mediate glutamate-induced migration of dissociated embryonic cortical cells in vitro. Reproduced with permission from Reiprich et al. (2005) (A) and Behar et al. (1999) (B). Scale bars in (A) correspond to 500 µm.