Table 1.
Gelation test results for amide derivatives I (6–14) and urea derivatives II (15–22).a
Compound | Structure | Hexane | Water | EtOH | Water/DMSO (2:1) | Water/EtOH (2:1) |
6 | ![]() |
I | G 10.0 | S | G 7.4 | G 8.0 |
7 | ![]() |
I | I | G 10.0 | G 4.0 | G 4.0 |
8 | ![]() |
C | C | G 20.0 | G 5.4 | G 6.0 |
9 | ![]() |
I | I | G 20.0 | G 5.7 | G 5.7 |
10 | ![]() |
I | I | G 10.0 | G 4.6 | G 8.0 |
11 | ![]() |
C | C | G 20.0 | G 5.0 | G 8.8 |
12 | ![]() |
C | I | S | G 6.0 | G 7.4 |
13 | ![]() |
I | G 2.0 | G 8.0 | G 5.7 | G 10.0 |
14 | ![]() |
C | I | G 10.0 | G 20.0 | G 10.0 |
15 | ![]() |
I | I | G 10.0 | G 4.0 | G 2.0 |
16 | ![]() |
I | P | G 5.0 | G 2.0 | G 2.0 |
17 | ![]() |
P | I | G 5.0 | G 4.0 | G 3.3 |
18 | ![]() |
C | I | G 10.0 | G 5.0 | G 5.0 |
19 | ![]() |
I | I | G 2.5 | G 2.0 | G 1.3 |
20 | ![]() |
P | I | G 3.3 | G 4.0 | G 4.0 |
21 | ![]() |
I | I | G 6.6 | G 2.8 | G 5.0 |
22 | ![]() |
I | I | G 20.0 | G 4.0 | G 5.0 |
aG, stable gel at room temperature, the number after G is the minimum gelation concentration (MGC) in mg/mL; I, insoluble; C, crystallization; P, precipitate; S, soluble at 20 mg/mL.