FIGURE 11.

Mitochondrial dehydrogenase (WST-1) assay for human retinal pigment epithelial cells after 24-hour exposure to dexamethasone solution (Dex-S), dexamethasone powder solubilized in DMSO (Dex-P), DMSO at an equivalent dose to solubilize the powder, and untreated controls. There was a reduction in mitochondrial dehydrogenase in all groups compared to untreated controls (P<.001). Cells treated with 1.0 mg/mL Dex-P had significantly higher mitochondrial dehydrogenase activity when compared to cells treated with Dex-S at the same concentration (P<.01).