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Fate of a preformed transferrin corona in vivo. A, activity of 59Fe and 125I (1–120 min) in blood; B and C, activity of 59Fe and 125I in organs 120 min after i.v. injection of 59Fe-SPIOs with a preformed protein corona of adsorbed (A,B right side) or covalently bound (A,B, left side) 125I-mouse-transferrin.
