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. 2015 Jan;54(1):35–39.

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Figure 2. — (A) ACTH concentrations in blood collected 30 min after the last handling bout or injection. ACTH was significantly (P < 0.01) higher in Sprague–Dawley rats than in Lewis rats, but ACTH concentration did not differ between handling groups. Error bars represent 1 SD. (B) Scatter plot showing individual ACTH concentrations. Sprague–Dawley rats showed greater interindividual ACTH variability than did Lewis rats, whose concentrations remained consistent across handling groups. In addition, Lewis rats showed a decrease in interindividual variability after extended handling. L, Lewis; S, Sprague–Dawley. NH, no handling; SH, short handling; LH, long handling; SI, saline injection.