Table 2.

Two-sample t-test differences between OSAs and GSs using ALFF method

Conditions	Brain regions	V (mm3)	t-score of peak voxel	MNI coordinates of peak voxel			P
OSAs < GSs	Right precuneus/posterior cingulate gyrus	1,350	−5.44	0	−51	30	<0.001*
OSAs > GSs	Left inferior frontal gyrus	297	5.37	−27	39	−21	<0.001*

Notes: The between-condition statistical threshold was set at cluster size with P<0.05, voxel with P<0.001, and V ≥270 mm³, corrected by FDR. P*, independent samples t-tests;

^*P<0.05.

Abbreviations: ALFF, amplitude of low-frequency fluctuation; FDR, false discovery rate; GSs, good sleepers; MNI, Montreal Neurological Institute; OSAs, patients with severe obstructive sleep apnea; V, volume.