Table 1.

Sample characteristics

	HC (n = 9)		PAE (n = 11)
	Mean/%	SD	Mean/%	SD	P‐value
Infant characteristics
Sex (% female)	33.3		54.5		0.075†
Gestational age at birth (week)	38.7	1.9	38.6	2.0	0.939
Postpartum age at scan (week)	3.0	1.6	2.6	1.5	0.589
Postconception age at scan (week)	41.6	2.1	41.2	2.3	0.658
Birthweight (g)	2753.3	478.4	2754.1	413.5	0.997
Head circumferencea (%ile for age)	44.2	28.2	22.4	19.2	0.063†
Maternal characteristics
Maternal age at delivery (year)	24.0	4.7	29.8	4.6	0.012*
Parity	1.2	1.2	2.3	1.5	0.105
Educationb (year)	10.6	0.9	9.7	1.0	0.807
Marital status (% married)	33.3		18.2		0.176
Smoking (cig/day)	4.3	2.5	6.5	4.8	0.218
Marijuana (days/week)	0.0	0.1	0.2	0.5	0.509
Extent of alcohol consumption
At conception
oz AA/dayc	0.02	0.05	2.25	1.89	0.002**
oz AA/occasionc	0.13	0.38	4.70	3.51	0.001**
Frequency (days/week)	0.02	0.05	0.42	0.30	0.001***
Across pregnancy
oz AA/dayc	0.01	0.03	1.68	1.52	0.004**
oz AA/occasionc	0.13	0.40	4.66	1.35	0.000***
Frequency (days/week)	0.01	0.03	0.33	0.26	0.001**
Infant global parameters
Number of DWIsd	21.7	4.4	22.4	3.6	0.698
Total intracranial volume (cm3)	469.4	60.8	434.6	43.5	0.152
WM volume (cm3)	200.7	23.0	182.9	25.6	0.123
WM fraction	0.43	0.04	0.42	0.03	0.535

HC = healthy control; PAE = prenatal alcohol exposure; SD = standard deviation; AA = absolute alcohol; ^† P < 0.10; *P < 0.05; **P < 0.01; ***P < 0.001.

^aMeasures from infant follow‐up assessment at 6.5 months of age; value missing for one PAE newborn.

^bEducation missing for one HC mother.

^cMeasures of oz AA for one PAE mother were winsorized (Winer, 1971).

^dNumber of DWIs remaining after deletion of any dropout/motion‐corrupted volumes.