Table 4.

Relation of prenatal alcohol exposure and other predictors to the DTI and physical outcome measures in the WM‐ROIs in each of the networks

		FA			MD			AD			PD
Network	Pred.	βmed	F(dfN, dfD)	P	β med	F(dfN, dfD)	P	β med	F(dfN, dfD)	P	β med	F(dfN, dfD)	P
CCCR
	Alc				−0.70	8.6 (1, 14)	0.011 *	−0.72	14.0 (1, 14)	0.002 **
	Cig							−0.27	2.5 (6, 9)	0.101	0.47	3.5 (1, 14)	0.083
	Mat. age				0.56	5.5 (1, 14)	0.034 *	0.53	6.3 (1, 14)	0.025 *
L‐PROJ
	Alc				−0.41	3.9 (10, 140)	0.000 ***	−0.52	4.1(10, 140)	0.000 ***
	Cig	0.12	4.2 (11, 4)	0.091							0.52	4.0 (1, 14)	0.066
	Mat. age				0.37	4.4 (1, 14)	0.056	0.44	6.5 (1, 14)	0.023 *
R‐PROJ
	Alc				−0.41	1.9 (12, 168)	0.035 *	−0.45	2.7 (12, 168)	0.002 **
	Cig										0.48	3.4 (1, 14)	0.085
	Age	0.33	8.6 (13, 2)	0.109	−0.41	5.8 (1, 14)	0.031 *	−0.39	5.3 (1, 14)	0.038 *
	Mat. age	−0.16	9.2 (13, 2)	0.103
	Sex				−0.20	4.3 (1, 14)	0.056	−0.39	5.9 (1, 14)	0.029 *
L‐ASSOC
	Alc				−0.65	6.0 (7, 8)	0.011 *	−0.66	8.1(1, 14)	0.013 *
	Cig										0.49	3.6 (1, 14)	0.080
	Age							−0.16	2.5 (6, 84)	0.030 *
	Mat. age				0.44	3.8(1, 14)	0.071	0.43	4.7 (1, 14)	0.048 *
R‐ASSOC
	Alc	0.23	1.8 (7, 98)	0.090	−0.62	10.2 (1, 14)	0.007 **	−0.67	14.1(1, 14)	0.002 **
	Cig							−0.29	3.9 (1, 14)	0.068	0.5	3.5 (1, 14)	0.082
	Age							−0.05	5.5 (8, 7)	0.018 *	−0.22	5.6 (8, 7)	0.018 *
	Mat. age	−0.10	2.3 (7, 98)	0.035 *	0.43	4.5 (1, 14)	0.053	0.40	5.7 (1, 14)	0.032 *
	Sex	0.18	2.5 (7, 98)	0.020 *							0.13	2.0 (7, 98)	0.068

F‐values are shown with final degrees of freedom of numerator (df_N) and denominator (df_D). Median standardized β‐values were calculated from the additional multivariate regressions of each network's individual WM‐ROIs (Tractographic Connections Section). Only predictors exhibiting effects at P ≤ 0.10 are shown. *P < 0.05; **P < 0.01; ***P < 0.001. alc = frequency of maternal drinking; age = infant age since conception; sex: male = 1, female = 2; cig = maternal smoking (cig/day); mat. age = maternal age at delivery.