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. Author manuscript; available in PMC: 2015 Jan 30.
Published in final edited form as: Nat Commun. 2014 May 20;5:3840. doi: 10.1038/ncomms4840

Figure 3. Soluble RA levels are higher in the distal half of the BPs at E10.

Figure 3

Bright-field images of LacZ expression in RA reporter cells (F9-RARE-LacZ) that were co-cultured with proximal (a) and distal halves (b) from the same E10 BP. Many cells in the vicinity of the distal samples were positive for the blue LacZ signal while few in the vicinity of the proximal sample were. (c) E10 retinal tissue was used as a tissue control. (d) As pharmacological controls, reporter cells in separate wells were exposed to 0 nM, 5nM and 100 nM RA. Scale bar, 1mm.