FIG 1.
Sequence analysis of TbRGG3. ClustalW alignment of TbRGG3 from T. brucei (Tb927.3.1820) with homologues from T. congolense (TcIL3000.0.25010), T. vivax (TvY486_0301090), and T. cruzi (Tc00.1047053510091.110). The underlined segment at the N terminus indicates the predicted mitochondrial import sequence identified using the MitoProt II program. Highlighted in red is the previously misannotated start codon within the mitochondrial import sequence. Green arginine (R) residues represent the 14 methlyarginine residues recently reported (47). An asterisk indicates identical amino acids, a colon indicates similar amino acids with strongly similar properties, and a period indicates similar amino acids with weakly similar properties.