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. 2015 Jan 30;10(1):e0117018. doi: 10.1371/journal.pone.0117018

Table 3. Descriptive statistics and results from simple logistic regression analyses for potential predictors of future falls and/or near falls.

Independent variables 1 No falls or near fallsn = 78 Falls and/or near fallsn = 63 Simple logistic regression analyses
OR (95% CI) P value
Age (years) mean (SD) 66 (10.4) 70 (8.3)
Female gender, n (%) 30 (38) 35 (56)
PD-duration (years), median (q1–q3) 2 (5–5) 4 (1–8) 1.12 (1.03–1.22) 0.011
Cognition (MMSE), median (q1–q3) 28 (26–29) 2 27 (26–29) 1.20 (1.01–1.42) 0.034
Motor symptoms (UPDRS III), median (q1–q3) 11.5 (7–15) 18 (10–23) 1.13 (1.07–1.2) <0.001
Dyskinesia (UPDRS IV item 32), n (%) a 22 (29) 3 24 (38) 1.51 (0.74–3.07) 0.255
Balance (BBS), median (q1–q3) 55 (52–56) 50 (42–54) 1.20 (1.11–1.30) <0.001
Comfortable gait speed (10MWT) (m/s), mean (SD) 1.24 (0.22) 1.02 (0.31) 21.92 (5.3–90.44) <0.001
Fatigue (FACIT-F), median (q1–q3) 41.5 (36–47) 31.5 (23–41) 1.11(1.06–1.16) <0.001
Pain, n (%) 15 (19) 25 (40) 2.76 (1.30–5.89) 0.008
Walking difficulties (Walk-12G), median (q1–q3) 6 (2–10) 17 (9–25) 1.12 (1.07–1,17) <0.001
Fear of falling (FES[S]), median (q1–q3) 127 (117–130) 3 88 (60–122) 3 1.03 (1.02–1.05) <0.001
History of falls past 6 months, n (%) 9 (11.5) 25 (40) 5.04 (2.14–11.90) <0.001
History of near falls, n (%) 13 (17) 37 (59) 7.12 (3.27–15.50) <0.001
Balance problems while dual-tasking, n (%) 26 (33) 42 (67) 4.00 (1.92–8.09) <0.001
Need help from others in daily activities (PADLS), n (%) b 1 (1.3) 2 12 (19) 17.88 (2.55–141.80) 0.006
Freezing of gait (item 3, FOGQsa), n (%) c 19 (25) 2 39 (62) 4.96 (2.40–10.25) <0.001
Turning hesitations (item 6, FOGQsa), n (%) d 16 (21) 2 33 (52) 4.19 (2.00–8.79) <0.001
Retropulsion (NRT), n (%) e 11 (14) 24 (38) 3.75 (1.66–8.47) 0.001

1 For the regression analysis, scores were adjusted to be in the same direction: higher scores = more problems.

2 One missing value

3 Two missing values

a Item 32 of the UPDRS part IV. Those scoring ≥1 were categorized as having dyskinesias.

b Those scoring >2 on the PADLS were categorized as needing help from others in daily activities.

c Item 3 (“freezing”) of the FOGQsa. Those scoring ≥1 were categorized as freezers.

d Item 6 (“turning hesitations”) of the FOGQsa. Those scoring ≥1 were categorized as having turning hesitations.

e Scores ≥1 on the NRT were categorized as having retropulsion

Wald test

BBS, Berg Balance Scale; FACIT-F, the Functional Assessment of Chronic Illness Therapy—Fatigue; FES(S), Falls Efficacy Scale, (Swedish version); FOGQsa, Freezing of Gait Questionnaire, self-administered version; MMSE, Mini Mental State Examination; NRT, Nutt Retropulsion Test; PADLS, the Parkinson’s disease Activities of Daily Living Scale; q1–q3, 1st-3rd quartile; SD, standard deviation; UPDRS III, part III (motor score) of the Unified Parkinson’s disease Rating Scale; UPDRS IV, part IV (complications of therapy), item 32; 10MWT, 10-Meter Walk Test; m/s, meters per second; Walk-12G, 12-item generic walking scale.