Figure 6. LZD decreased PVL toxin levels in lungs post bacterial challenge as compared to Vanco or saline treated animals.

WT mice were infected with H1N1 100 pfu i.n. and on day 7 challenged with 5×10⁷ cfu cMRSA i.t., infected mice were treated with either vehicle or antibiotics LZD (80mg/kg i.p.) or Vanco (110 mg/kg i.p.). Lungs were harvested 24 hours post bacterial challenge and homogenized to single cell suspension, PVL protein levels were measured by western blot analysis and densitometry using Image J software. n = 4 in each group, experiments repeated twice. *p < 0.05, τ < 0.001 as compared to vehicle treated group.