Table 2.
Relationship between clinicopathological characteristics and overall survival in patients undergoing surgery for stage II colon cancer: univariate and multivariate analysis
| Risk factor | Patients (n = 871) | Univariate HR (95% CI) | P-value | Multivariate HR (95% CI) | P-value |
|---|---|---|---|---|---|
| Age in years (<75/≥75) | 535/336 | 2.69 (2.18, 3.33) | <0.001 | 2.64 (2.1, 3.3) | <0.001 |
| Gender (Male/Female) | 426/445 | 0.86 (0.69, 1.06) | 0.146 | ||
| Deprivation1 (intermediate) (deprived) | 134/499/238 | 1.19 (0.86, 1.66) | 0.288 | ||
| 1.35 (0.95, 1.92) | 0.095 | ||||
| Mode of presentation (elective/emergency) | 662/209 | 1.63 (1.30, 2.05) | <0.001 | 1.70 (1.36, 2.14) | <0.001 |
| Specialization (yes/no) | 580/291 | 1.21 (0.98, 1.51) | 0.081 | ||
| Leak (no/yes) | 855/16 | 1.00 (0.44, 2.24) | 0.994 | ||
| Chemo (no/yes) | 760/111 | 0.56 (0.39, 0.82) | 0.003 | 0.83 (0.56, 1.23) | 0.352 |
1
Baseline—affluent.