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. Author manuscript; available in PMC: 2016 Jan 1.
Published in final edited form as: Biomaterials. 2014 Oct 31;37:456–468. doi: 10.1016/j.biomaterials.2014.10.044

Fig. 9.

Fig. 9

(A) The body weight changes for animals treated with TM(CDDP/PTX = 2:1) at two dosage levels, e.g. 4 and 6 mg CDDP/kg for three dosage in MTD study; (B) the body weight changes of animals treated with a single dose of free drug mixture of CDDP/PTX 2:1 w/w and TM(CDDP/PTX = 2:1) at 10 mg CDDP/kg level in comparison with PBS control group; (C) the serum AST and ALT enzyme levels and BUN level of animals in the acute toxicity studies treated with free CDDP/PTX and TM(CDDP/PTX = 2:1), respectively, at 10 mg CDDP/kg level; The blood cell counting analysis for WBC (D), PLT (E) and RBC (F) for the mice in MTD and acute toxicity studies. (*p < 0.05).