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. Author manuscript; available in PMC: 2016 Jan 1.
Published in final edited form as: Biomaterials. 2014 Oct 31;37:456–468. doi: 10.1016/j.biomaterials.2014.10.044

Fig. 8.

Fig. 8

(A) In vivo pharmacokinetics profiles of platinum concentration in the plasma after i.v. administration of free CDDP and TM (CDDP/PTX). (B) Tissue distribution of platinum concentration in the plasma on day 2 after i.v. administration of free CDDP and PB-CDDP-PTX. Each drug was administered to Nude mice bearing human SKOV3 ovarian cancer tumor (female, n = 3) at a dose of 6 mg/kg on CDDP basis. Data were expressed as mean ± SE (**p < 0.01; ***p < 0.005).