Table 1.

Protein down-regulated in NgBR knockdown tumor cells

Category	Accession number	Gene name	Protein Description	Protein abundance ratio
				KD1/NS1	KD2/NS2
Extracellular markers	IPI00297160.4	CD44	cell surface glycoprotein CD44	0.180	0.189
	IPI00011302.1	CD59	cell surface glycoprotein CD59	0.393	0.698
	IPI00298851.4	CD151	cell surface glycoprotein CD151	0.312	0.309
	IPI00179700.3	HMGA1	Isoform HMG-I of High mobility group protein	0.519	0.385
Cytoskeleton proteins	IPI00418471.6	Virmentin	intermediate filament protein	0.520	0.747
	IPI00008603.1	ACTA2	aortic smooth muscle actin	0.613	0.812
	IPI00032313.1	S100A4	Calcium-binding protein S100A4	0.260	0.546
	IPI00027463.1	S100A6	Calcium-binding protein	0.524	0.461
	IPI00183695.9	S100A10	Calcium-binding protein	0.314	0.598
	IPI00013895.1	S100A11	Calcium-binding protein	0.423	0.338
	IPI00218918.5	ANXA1	Annexin A1	0.553	0.345
	IPI00418169.3	ANXA2	annexin A2 isoform 1	0.394	0.289
	IPI00024095.3	ANXA3	Annexin A3	0.393	0.239
	IPI00002459.4	ANXA6	annexin VI isoform 2	0.630	0.485
	IPI00008868.3	MAP1B	Microtubule-associated protein 1B	0.312	0.463
	IPI00302592.2	FLNA	Isoform 2 of Filamin-A	0.480	0.420
	IPI00289334.1	FLNB	Isoform 1 of Filamin-B	0.464	0.468
	IPI00178352.5	FLNC	Isoform 1 of Filamin-C	0.474	0.717
GT Pases	IPI00005719.1	RAB1A	Isoform 1 of Ras-related protein Rab-1A	0.583	0.527
	IPI00016339.4	RAB5C	Ras-related protein Rab-5C	0.583	0.427
	IPI00020436.4	RAB11B	Ras-related protein Rab-11B	0.599	0.648
	IPI00007189.1	CDC42	Isoform 1 of Cell division control protein 42 homolog	0.629	0.805
	IPI00010270.1	RAC2	Ras-related C3 botulinum toxin substrate 2	0.574	0.550
	IPI00027434.1	RHOC	Rho-related GTP-binding protein RhoC	0.646	0.694