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Histograms of the ZZZ/ZXX and XZX/ZXX ratios determined by polarization-resolved SHG for type-I vs. type-II collagen. The histograms show that a strong discrimination between these collagen types can be achieved. 2-D images of these ratios for collagen-I dominated rail tail tendon (left column) vs. type-II dominated rat trachea (right column) shows consistent differences. Reproduced from Su et al. (36) with permission. SHG, second harmonic generation.
